Epigenetic Regulation of the circadian clock
gene Per1 in memory and aging
Janine Kwapis, Ph.D.
Assistant Professor, Department of Biology Pennsylvania State University
In this talk, I will present evidence that the circadian gene Period1 (Per1) serves as a key interface between the circadian clock and memory formation. Our work shows that hippocampal Per1 modulates memory formation and age-related repression of Per1 contributes to age-related memory decline. Learning-induced increases in Per1 correlate with memory formation across the diurnal cycle, consistent with the idea that Per1 functions to “gate” memory formation across the 24h day.
This event is being conducted over Zoom. As the host, Mount Holyoke College reserves the right to record this session and the event sponsors will give prior notification to event participants of any intention to do so. The recording feature for others is disabled so that no one else will be able to record this session through Zoom. At all times, no recording by any other means is permitted without prior written permission from the event sponsor or as an approved accommodation.
Tuesday, February 23 at 4:30pm to 6:00pmVirtual Event